Columbia

Columbia

Columbia is the South Carolina capital, USC Gamecock country, and home to one of the largest urban rivers (the Congaree) flowing right past downtown. The Saluda River outside town is a tubing destination locals swear by, and Congaree National Park's old-growth cypress is a 30-minute drive. The state museum is a sleeper good time. Slower-paced than Charleston, less touristy.

Huntsville

Huntsville is Rocket City, with NASA's Marshall Space Flight Center, the Saturn V rocket on display at the Space and Rocket Center, and a tech and engineering economy that punches way above the city's size. Cummings Research Park is the second-largest research park in the U.S. The Tennessee River and Monte Sano State Park give it a quiet outdoor side. Affordable and surprisingly smart.