San Francisco

San Francisco

San Francisco is hills, fog, Mission burritos the size of forearms, and pastel Victorians stacked like dominoes. Karl the Fog has his own Instagram, the cable cars are still mechanically pulled by cables running under the street, and the Pacific shows up at the end of every west-bound avenue. The food is wildly good, the views are theatrical, and yes, you'll get cardio just walking to the corner store.

Knoxville

Knoxville is the gateway to the Great Smoky Mountains (the most-visited national park in the country, 30 minutes east), the University of Tennessee's Vol energy, and the gold-roofed Sunsphere left over from the 1982 World's Fair. Market Square downtown is brick, patios, and a Saturday farmers market that takes over the whole space. The food and bar scene has come into its own. The mountains do the heavy lifting.