San Jose

San Jose

San Jose is Silicon Valley's anchor city, much bigger than San Francisco by population, and culturally underrated because everyone drives through it on the way somewhere else. The Vietnamese food scene (especially in Little Saigon) is one of the best in the country. The weather is impossibly mild, the Santa Cruz Mountains rise to the west, and the tech money funds a genuinely excellent restaurant scene.

Greensboro

Greensboro was the site of the 1960 Woolworth sit-in (the original lunch counter is preserved at the International Civil Rights Center and Museum, downtown). Four major colleges feed the city, the food scene leans BBQ and good coffee, and the surrounding Piedmont rolls gently in every direction. It's the geographic center of North Carolina, which makes it a useful base for everything else in the state.