San Luis Obispo

San Luis Obispo

San Luis Obispo (SLO to locals) sits halfway between LA and San Francisco on the central coast, with Cal Poly students, gorgeous wine country (Edna Valley and Paso Robles nearby), and a Thursday night farmers market that takes over downtown. It's been called the happiest city in America (multiple studies, Oprah included), and the vibe really does back that up. Bubblegum Alley is exactly what it sounds like. Mellow and beautiful.

San Antonio

San Antonio wraps the River Walk through downtown like a Venetian canal trail (much shorter, but lined with mariachi and margaritas). The Alamo sits in the middle of it all, the five Spanish missions are a UNESCO World Heritage Site, and the puffy tacos are unlike Tex-Mex anywhere else. Fiesta in April is essentially a 10-day citywide block party. It's bigger and prouder than outsiders expect.